He watched his daughter break the entire newly built lighthouse. “What’s wrong with it?” “There’s no balcony,” she muttered. As she crushed the beautiful white tower, her dad pointed out. “It resembled Fastnet. You could’ve just added a few circular railings at the top and- “ “I want two balconies.” She’d made up her mind. The dad shook his head and sipped his morning coffee, reading the newspaper. He wondered if using LEGO instead of CADD would help him in his quest for better drug designs. Maybe LEGO wasn’t such a bad idea after all. He imagined the day when designing new drugs would be as simple and creative as building with those little tiny pieces. He’d still have to work out multiple permutations of different blocks, hoping he would find the perfect combination for a drug that could possibly help millions around the globe . This is where the latest breakthrough in structure-based generative chemistry comes into play. The Puzzle of Drug Design Have you...